Biologic Therapies and New Treatments for Lupus
Recent studies are demonstrating promising results for nipocalimab, a monoclonal antibody that has shown effectiveness compared with placebo.
Understanding the New Treatment Recommendations for Systemic Lupus
The American College of Rheumatology (ACR) has established updated recommendations for the treatment of systemic lupus erythematosus (SLE). The overall goal of treatment is to control lupus [...]
A Guide to Conducting Car T-Cell Trials for Patients With SLE
T-cells can be very helpful in the treatment of autoimmune disease as well as different types of cancer.
New Hope for Lupus Nephritis: FDA-Approved Medications Explained
Food and Drug Administration (FDA) has approved several therapies specifically for lupus nephritis (LN). These drugs have been studied in clinical trials and shown to help protect kidney function [...]
CAR-T Therapy for Complicated Lupus (Experimental Use)
If you follow lupus research, you may have heard about CAR-T cell therapy—an innovative treatment approach currently being investigated for people with complicated, refractory systemic lupus [...]
A Liquid Biopsy for Lupus Nephritis?
A liquid biopsy for kidney lupus is being developed. It relies on determining levels of tenascin C in the urine. It’s a predictor of kidney function loss in lupus. – Dr. Robert Katz, LSI's Board [...]
FDA Approves Genentech’s Gazyva for the Treatment of Lupus Nephritis
FDA approval based on superiority of Gazyva over standard therapy alone, as shown in Phase II NOBILITY and Phase III REGENCY data –
Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
According to new research (Law, et. All, Nature, 2024), it may be that T lymphocytes appear to play a more important role than we thought in causing active lupus. They […]
Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
Recent lupus research has received significant coverage bringing encouraging results. The research was partially funded by the Lupus Research Alliance (LRA) – an organization the LSI [...]
Role of Lupus Patient Support
By Irene Blanco, MD, MSProfessor of Medicine-Rheumatologyco-Director of the Clinical Research Ethics & Equity Consultative Service (CREEC) Lupus can have long-term consequences on patients’ [...]
